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Seminar ANTONIO ROSATO on 15/02/16

Natural polymers as carriers of cytotoxic drugs, cytokines and immunogens.
Noticeboard Type: 
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When: 
02/15/2016 - 02/15/2016

Prof. Antonio ROSATO, MD, PhD
University of Padua
Dept. Surgery, Oncology and Gastroenterology
Padua, Italy

Monday, 15 February 2016 - 12:00
Seminar room, I floor, Q Building – Via Giorgieri 5

Host: prof. Giannino del Sal

Natural polymers (NP), and in particular hyaluronan, are usually biodegradable, biocompatible, non-toxic, non-immunogenic and noninflammatory,
and play pivotal roles in wound healing, cell motility, angiogenesis as well as construction and integrity of extracellular matrix. Because of various biological functions and excellent physicochemical properties, NP and their derivatives are widely employed for long-acting delivery applications of nucleotide, peptide and protein therapeutics. Along several years, we were prompted to explore the potentiality of NP as carrier of cytotoxic drugs and cytokines for cancer
therapy. The lecture will provide an overview of past and ongoing research activities, with a particular focus on an emerging role for NP as a new class of TLR agonists and vaccine adjuvants for the induction of safer and more efficient immune responses.

Last updated on: 05/06/2021 - 11:41