In normal physiology, cells generate and sustain mechanical forces. They are active materials that can detect mechanical stimulation by the activation of mechanosensitive pathways and react to physical signals through cytoskeletal re-organization and force generation. Genetic mutations and pathogens that disrupt the cytoskeletal architecture can result in changes to cell mechanical properties such as elasticity, adhesiveness, and viscosity. (...)
Last updated on: 07/06/2018 - 13:40